Advanced Diagnostic Laboratories

D-Dimer

Test Code

DDIME

Description

D-Dimer, Quantitative - D-Dimer is one of the measurable by-products of activation of the fibrinolytic system. Quantitation of D-Dimer assesses fibrinolytic activation and intravascular thrombosis. D-Dimer is of particular value in excluding the diagnosis of venous thromboembolism among patients at high risk.

Collect

Sodium Citrate Plasma (Light Blue Top) 2.7 mL Vacutainer
Must fill to Mininum-Fill mark on tube

Pediatric Collection

Fill to Minimum Fill Indicator on draw tube

Unacceptable Conditions

Clotted Specimen, Insufficient Specimen, Hemolysis

Storage Transport Temp

Storage Transport Temp

Offsite: Specimens collected offsite should be separated from cells within 2 hours of centrifugation and an aliquot placed in appropriately labeled polypropylene or similar plastic tube.

Onsite: Specimens must be transported within 1 hour to the clinical laboratory for processing and testing.

Stability

Notes

Light blue top tube requires a minimum volume to assure proper ratio of anticoagulant to whole blood

Performed

Monday - Friday

Methodology

Turbidimetric Immunoassay

Turnaround Time

1 hour STAT or routine

Department

Core Lab

Synonyms

D-Dimer, DIMER

Study Offerings

Not offered

Reference Interval

Age ≤50 years : D-Dimer, quantitative: <0.50 ug/mL FEU
Age >50 years : PE/DVT Index: Normal

Interpretation

For patients greater than 50 years old, age adjusted cutoff interpretation is applied using the calculation: age x 0.01 ug/mL FEU and reported as a qualitative PE/DVT index (Normal/Abnormal) with regards to exclusion for suspected thrombosis. Patients 50 years or older have an association with increased diagnostic yield of non-specific D-Dimer.