Blood Lymphocyte Stimulation with Beryllium
Test Code
BELPT
From December to April, and on extreme cold temperature days outside of these months, please follow these recommedations:
- Ensure that a minimum of 40 mL of whole blood is sent to the laboratory.
- Add extra insulation around sample tubes, such as paper towels, cold packs warmed to room temperature, or any other insulating item that will protect samples from winter weather conditions.
- Ship via priority overnight courier
Description
The beryllium lymphocyte proliferation test (BeLPT) is the gold standard screening tool for workers who are exposed to beryllium. This simple blood test identifies beryllium sensitization and is recommended for workers with exposure to any form of beryllium dust or fumes – including pure beryllium metal, copper-beryllium alloys, aluminum-beryllium alloys, nickel-beryllium alloys, recycled scrap containing beryllium, ceramics and composite materials. Exposure to beryllium can be harmful and can cause health effects such as beryllium sensitization (BeS) and chronic beryllium disease (CBD).
Occupational Safety and Health Administration (OSHA) and the Department of Energy both require workers receive beryllium lymphocyte proliferation testing as part of their medical surveillance exams.
Collect
Collect 30-40 mL of blood in green (sodium heparin) topped tubes. Gently invert several times to mix and prevent clotting. DO NOT centrifuge.
Patient Prep
POSITIVE PATIENT IDENTIFICATION [Labeling] requires we use two (2) pieces of information [identifiers].
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Both identifiers must match exactly on the specimen label and the requisition/order that corresponds to that specimen.
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Where appropriate for multiple samples submitted together, specimen collection information (e.g. site or source, date and time of collection, etc.) must also be included on the specimen label.
Unacceptable Conditions
Centrifuged specimens, specimens received after 30 hours of draw, frozen specimens.
Storage Transport Temp
Send ambient blood Priority Overnight via FedEx or UPS in a well insulated container (or in the ADx shipping kit). Specimen must be received in the laboratory within 30 hours of collection.
Stability
AMBIENT: 30 HOURS
Note: Samples shipped from New York State must be received within 24 hours of collection.
Notes
For more than 10 patient samples, ADx Client Services must be called at 800.550.6227 to schedule testing before sample is shipped. Please include the number of specimens you anticipate sending. We accept samples Monday through Saturday.
Performed
Monday - Sunday
Methodology
Lymphocyte stimulation in cell culture
Turnaround Time
14 days
Department
Immunology Lab - Functional Assay
Synonyms
Lymphocyte Proliferation (Beryllium Lymphocyte Stimulation, Blood), BeLPT, Metals (Beryllium Lymphocyte Stimulation, Blood), LPT, BER1, belpt, ber1, BE Order Set, beryllium transformation
Study Offerings
Not offered
Related Tests
Lymphocyte Proliferation Assessment: (begin with Lymphocyte enumeration, CDC panel, TBCDC), Lymphocyte proliferation to candida antigen (LSCAN), Lymphocyte proliferation to ConA mitogen (LSCON), Lymphocyte proliferation to PHA mitogen (LSPHA), Lymphocyte proliferation to PWM mitogen (LSPWM), Lymphocyte proliferation to tetanus antigen (LSTET)
Reference Interval
Normal
CPT Code
86353
New York Approved
Standard
FDA
LDT