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Healthy Participants Needed for Lung Inflammation Study

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Trial Objectives


Inflammation in the lungs is tied to a number of diseases, including pneumonia and acute respiratory distress syndrome (ARDS). Researchers want to better understand how the lungs heal after patients have recovered from these conditions by studying the involvement of immune cells called macrophages.

Volunteers in this study will be randomly assigned to one of two groups. The first group will receive a treatment that will stimulate the immune cells in the lung and then receive a nasal brushing and bronchoscopy. The second group will receive the nasal brushing and bronchoscopy only. Researchers will use the information collected to develop therapies that can help the lungs heal more effectively.

Who Can Participate


Adults 18-50 with no prior history of lung or systemic diseases.  

Age: 18-50 Gender: Any

Estimated Time Commitment


Three study visits, with the first visit lasting 1-2 hours and last two lasting about 6-8 hours each.

Payment & Reimbursement


Payment: Provided

Travel Reimbursement: Not Available

Trial Contact


For more information, contact:

Beatrice Kwarteng
303.398.1553

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Trial Location


National Jewish Main Campus, Denver, CO

Trial Sponsors


National Institutes of Health (NIH)

Principal Investigators

Kara Mould

Kara Mould, MD, MPH

Co-Investigators

William J. Janssen

William J. Janssen, MD

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