Possible Treatment for Post-COVID POTS

Trial Objectives

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Postural Orthostatic Tachycardia Syndrome, or POTS, is a chronic condition that involves sudden, rapid increases in heart rate when sitting or standing.  This condition can disrupt daily life and trigger other symptoms such as fatigue, dizziness or vertigo. Research has linked POTS symptoms to long-haul COVID-19 infections, but the connection between these conditions is still being studied. In this clinical trial, researchers are evaluating if a research medication called IgPro20 can help improve symptoms of POTS in post-COVID patients.

Volunteers will be randomly assigned to receive either IgPro20 or a placebo (a medication containing no active ingredient) administered subcutaneously (under the skin). At clinic visits, volunteers will receive physical examinations and orthostatic assessments (a test that involves standing to measure heart rate and blood pressure), and will receive questionnaires about their symptoms in the clinic and at home.