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Our lab performs basic & translational research to understand the role of monocytes and macrophages in modulating airway inflammation in people with cystic fibrosis (CF).

 

Lab Resources & Services

The lab is located on National Jewish Health main campus.

 

Current Projects

  1. Characterization of macrophage populations in the CF airway, and investigations into how these cells modulate inflammation.

    • How much heterogeneity is present in airway macrophage populations?

    • Does the abundance of populations of macrophage shift during pulmonary exacerbations?

    • How do various medications affect airway macrophages phenotypes?

  2. Identification of novel therapeutics / anti-inflammatory medications for people with CF (and other chronic inflammatory airways diseases)

  3. Investigations into the role of macrophages in susceptibility of people with CF to NTM infection.

 

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Katherine Hisert

Katherine Hisert, MD, PhD

Publications

 

 

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