Allergy

At National Jewish Health, we are world leaders in allergic disease research, employing a multidisciplinary approach to tackle various allergic conditions. Our researchers have a long history of making groundbreaking discoveries, including the identification of the IgE molecule responsible for allergic reactions. Research programs encompass several key areas of focus and innovative approaches. Here is an overview of our allergic disease research programs:

• Allergy and Immunology Center: The center specializes in the comprehensive evaluation and treatment of allergic diseases, integrating research with clinical care to develop new therapies and improve patient outcomes. Our team conducts studies on the pathophysiology of allergies, including the role of immune system dysfunction, environmental triggers and genetic factors.
• Allergic Rhinitis Research: Our scientists investigate the mechanisms of allergic rhinitis, focusing on the role of specific allergens, immune responses and inflammatory pathways. Research aims to improve diagnostic methods and develop new treatment options, such as advanced immunotherapies and personalized medicine approaches.
• Allergic Asthma Research: We are studying the interplay between allergies and asthma, particularly the mechanisms of allergen-induced asthma, inflammation and airway remodeling. Key efforts involve developing targeted biologic therapies, optimizing current treatments and exploring new treatment strategies.
• Food Allergy Research: Our research seeks to understand the immunological basis of food allergies, refine oral immunotherapy protocols and explore novel treatments to reduce food allergy symptoms and improve patients' quality of life.
• Atopic Dermatitis (Eczema) Research: Investigators study the immunological and genetic factors contributing to eczema, assessing new topical and systemic treatments and improving our understanding of how eczema impacts overall health.
• Immunotherapy Research: A major focus is the development of novel allergen-specific immunotherapies, including sublingual and subcutaneous immunotherapy. We are also exploring combination therapies and new methods to enhance treatment efficacy.
• Genetic and Environmental Factors Research: Our researchers examine genetic predispositions and environmental factors that contribute to allergic diseases, aiming to identify biomarkers for early diagnosis and personalized treatment strategies. We investigate how allergic diseases impact patients' quality of life and explore strategies to improve the management and support of those with chronic allergic conditions.
• Collaborative Research: At National Jewish Health, we collaborate with other institutions, pharmaceutical companies and research organizations to enhance the scope and impact of our research. This includes multicenter studies and joint research initiatives.
• Clinical Trials and Novel Diagnostics and Treatments: Our teams are involved in clinical trials testing new drugs, biologics, and other treatments for allergic disorders. Research also includes developing and validating new diagnostic tools and biomarkers to improve the accuracy of diagnosing allergic diseases and monitoring disease progression.
• Allergic Disease Research Advancements: Oral food challenge to diagnosis food allergies and treatments. Blood test to diagnosis allergies to artificial joints.