Environmental and Occupational Lung Diseases

We are leaders in research on environmental and occupational lung diseases. National Jewish Health is committed to studying how environmental factors—such as air pollution, occupational exposures and climate change—affect lung health. Our research investigates the impact of these environmental toxins on the development and progression of chronic respiratory diseases, including asthma, COPD and interstitial lung diseases. The institution’s work aims to identify preventive strategies and therapeutic interventions for individuals at high risk due to environmental exposures. By raising awareness and developing evidence-based interventions, we seek to mitigate the harmful effects of these environmental risk factors on lung health. Here is an overview of our environmental and occupational lung disease research programs:

• Environmental and Occupational Lung Disease Center: The center specializes in the study and management of lung diseases caused by environmental and occupational exposures. It integrates clinical care with research to address the impact of these exposures on lung health. Research includes studying genetic predispositions that may influence an individual’s susceptibility to lung diseases caused by environmental and occupational factors. Our center investigates a wide range of environmental and occupational lung diseases, including asthma, chronic beryllium disease, sarcoidosis, chronic obstructive pulmonary disease (COPD), pneumoconiosis, and other conditions related to exposure to pollutants, dust and chemicals.
• Environmental Exposures Research: Our research on air pollution focuses on its impact on lung health, particularly the effects of particulate matter, ozone and other pollutants. Studies aim to understand how these exposures contribute to chronic lung diseases and exacerbate existing conditions. Another area of focus is indoor air quality, where our investigators research the health effects of indoor air pollutants such as tobacco smoke, mold and volatile organic compounds. The goal is to develop strategies to improve indoor air quality and mitigate health risks.
• Occupational Exposures Research: Our researchers study pneumoconiosis caused by exposure to dust, such as coal dust (black lung disease) and asbestos, to better understand their mechanisms and develop effective treatments. Another key area of research is the exploration of the effects of workplace chemical exposures, including solvents, pesticides, and industrial fumes, on lung health and disease progression.
• Collaborative Research: We collaborate with other research organizations, government agencies and academic institutions to advance research on environmental and occupational lung diseases. This includes participating in and leading multicenter studies and research initiatives to enhance the scope and impact of our research.
• Clinical Trials and Studies: At National Jewish Health, we conduct clinical trials to evaluate new interventions and treatments for diseases related to environmental and occupational exposures. This includes testing new medications, therapies and preventive measures.
• Environmental and Occupational Lung Disease Research Advancements: Identified hazardous chemical exposures associated with methamphetamine labs. Identified diagnostic biomarkers for risk of developing chronic beryllium disease in workers.