Chronic Obstructive Pulmonary Disease (COPD)

COPD research at National Jewish Health is groundbreaking, particularly in the areas of genetics, environmental exposures and clinical trials. Through large-scale genetic studies, we are uncovering the genetic underpinnings of COPD, which could lead to targeted therapies addressing the root causes of the disease. In addition, the institution leads numerous clinical trials aimed at improving COPD management by exploring both pharmacologic and non-pharmacologic interventions. We aim to reduce the burden of this chronic, progressive disease and improve outcomes for patients, particularly those with severe forms of COPD. Here is a look at some of our COPD research efforts:

• COPDGene Center: We lead the largest NIH-sponsored program examining genetic and clinical changes in the largest COPD patient cohort in the United States. Our COPD Center provides comprehensive care and conducts advanced research, focusing on both clinical and translational research to improve outcomes for patients with COPD.
• Research Programs: Our renowned researchers conduct innovative research in COPD, including studies on the role of inflammation, oxidative stress, and the genetic, environmental, and immunological factors that contribute to the disease. Research on genetic and epigenetic factors contributing to COPD susceptibility and progression is also a key area of focus. We also explore novel treatment approaches and interventions.
• Mah Jongg Foundation COPD Accelerator Program
• Collaborative Efforts: Our researchers work closely with other institutions, pharmaceutical companies and academic centers to advance COPD research. These collaborations leverage a wide range of expertise and resources to accelerate discoveries.
• Clinical Trials and Innovative Therapies: We conduct clinical trials to test new medications, therapies and devices aimed at improving COPD management. Long-term studies focus on understanding disease progression, identifying biomarkers and evaluating the effectiveness of various treatments over time.
• COPD Research Advancements
• Discovery of unique subtypes of COPD through work by COPDGene.